Mixed-Integer Optimal Control in Cardiology

Mixed-Integer Optimal Control problems combine difficulties of combinatorial decisions with underlying dynamical systems and are therefore known to be hard to solve. One approach to handle these problems is based on decomposition into a nonlinear and a mixed-integer program, where the latter involves ongoing potential for improved rounding methods. In cardiac electrophysiology, the discrimination of certain heart arrhythmia is complex so that reducing the task to an optimization problem enriches the medical practice (see, e.g. [1]). Similarly, cardiac biomechanics comprise difficult therapy decisions, e.g. Cardiac Resynchronization Therapy, where whole heart and circulatory system models are beneficial. In both areas, there is a lack of mature optimization techniques.

  • Dec 05th 2024, Torsten Reuter succesfully defended his PhD thesis on "D-optimal Subsampling Design for Massive Data"
  • Dec 03rd 2024, Xiangying Chen succesfully defended his PhD thesis on "Conditional Erlangen Program"

...more
  • Dec 05th 2024, Torsten Reuter succesfully defended his PhD thesis on "D-optimal Subsampling Design for Massive Data"
  • Dec 03rd 2024, Xiangying Chen succesfully defended his PhD thesis on "Conditional Erlangen Program"

...more